estratto dalla rivista "Allergy".
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European Polistes venom allergy (abstract)
M. G. Severino,
P. Campi, D. Macchia1, M. Manfredi2, S. Turillazzi, I. Spadolini,
M. B. Bil, F. Bonifazi
The American Polistes species venom mixture
– that of P. annularis, P. fuscatus, P. metricus and
P. exclamans – was the only commercially available mixture
for diagnosis and therapy until 1996.
However, these species of Polistes are not
present in Europe, where P. dominulus and P. gallicus and
to a lesser extent P. nimphus are widespread. The aim of this
study was to assess the allergenic differences among the commercial
American mix, P. dominulus and P. gallicus venom in European
patients and therefore to verify if this mixture is suitable
for diagnosis in these patients.
We carried out skin tests, radioallergosorbent tests (RAST)
and RAST inhibition in Italian patients with adverse reactions
to Polistes stings. RAST inhibition results demonstrated that
cross-reactivity between the American and European species
is only partial and that P. dominulus and P. gallicus venoms
have exclusive allergens.
Skin tests and direct RAST confrmed these results and also
showed that European Polistes venom is more suitable than
the American mix in Italian patients. Moreover, we found a
high rate of cross-reactivity between P. dominulus and P.
To conclude, P. dominulus and/or P. gallicus venoms are necessary
for diagnosis and therefore in the therapy of European patients.
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